Field Definitions

Social and Behavioral Sciences

Behavioral and social sciences research has a major and explicit focus on the understanding of behavioral or social processes and/or patterns, or on the use of these processes and/or patterns to predict of influence health outcomes or health risk factors. “Behavioral” refers to overt actions; to underlying individual psychological processes such as cognition, emotion, temperament, and motivation; and to biobehavioral interactions. The term “social” encompasses sociocultural, socioeconomic, and sociodemographic status; to biosocial interactions; and to the various levels of social context from small groups to complex cultural systems and societal influences. Social and Behavioral research may focus on prevention and/or care. Research findings may have implications for policy, social changes and systems changes.

Disciplines supporting such research include psychology, sociology, anthropology, demography, public health, epidemiology, medicine, etc.

Clinical Sciences

Clinical research is intended to understand the effects of medical treatments or methods on disease progression, the effects of medical treatments or methods on prevention or the effects of medical treatments or methods on diagnosis in patients. Such research includes therapeutic interventions, preventive vaccines, and testing of new technologies, often in a clinical trial format. Clinical research is research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena linked to medical treatments or methods) for which an investigator (or colleague) directly interacts with the study participants. Excluded from this definition are in vitro studies that utilize human tissues that cannot be linked to a living individual.

Disciplines supporting such research include medicine, infectious diseases, pharmacology, clinical immunology and others

Basic Biomedical Sciences

Basic biomedical research involves laboratory studies aimed at understanding the underlying mechanisms of disease at the cellular or subcellular level, or laboratory studies aimed at understanding the mechanism of action or optimization of treatments by conducting research at the cellular or subcellular level. For this purpose, basic biomedical research excludes clinical research conducted with human subjects or on material of human origin for which an investigator directly interacts with human subjects and includes in vitro studies that utilize human tissues that cannot be linked to a living individual.

Disciplines supporting such research include biochemistry, molecular biology, cell biology, microbiology including virology, immunology, structural biology, organic chemistry and others. Also included in this category is the development of novel therapeutics including novel drug development and gene therapy development, and the development of novel diagnostics.

Systems of Prevention and Care

Research on systems of prevention and care encompasses both basic and applied studies that examine access, availability, utilization, costs, quality, delivery, organization, policy and financing related to organizations and service delivery systems. This research is intended to produce new knowledge that can be applied to improve prevention and care services for affected persons and populations.

Disciplines supporting such research include health economics, organizational psychology, policy analysis, systems analysis, epidemiology, sociology, demography, medicine, and public health, et cetera.